PERSONALIZED APPROACH TO PATIENTS WITH STATIN INTOLERANCE BASED ON PHARMACOGENOMICS (FUNCTION OF OATP1B1 PROTEIN)

Personalized approach to patients with statin intolerance based on pharmacogenomics (function of OATP1B1 protein)

Statins, HMG CoA reductase inhibitors, are effective at lowering blood cholesterol levels and protecting against cardiovascular incidents.Their uptake into hepatocytes depends on the activity of the SLCO1B1 Girls Leggings gene which codes for the OATP1B1 transporter protein.Pharmacogenomic testing provides us information about the activity level of

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TOWARDS EGRESS MODELLING IN VOXEL BUILDING MODELS

Egress (or Evacuation) modelling has the purpose to simulate how the people inside a building can move outside in a safe manner and as quick as possible Cosmetic Set in case of an emergency.The goal can be to assess the safety of an existing building or a building design, to establish evacuation routes and install signage, or even to give real-time

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Adverse skin reactions to antiepileptic drugs - a review

Introduction and objective: Treatment with antiepileptic drugs (AEDs) is frequently used all around the world.Just like in the course of all the drugs administration, side effects may appear, including characteristic side effects presenting on the skin.The aim of the study was to analyse adverse skin reactions to antiepileptic drugs, focusing on th

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